Product: AM05431PU-SAdrenocorticotropic Hormone (ACTH) (1-24) antibody
Quantity: 0.2 mg
Synonyms: Adrenocorticotropic hormone, Corticotropin, POMC
Presentation: Aff – Purified
Clonality: Monoclonal
Host: Mouse
Isotype: IgG1
CAS NO: 74115-01-8 Product: SKF-82958 (hydrobromide)
Shipping to: Worldwide
Immunogen: Synthetic peptide corresponding to the amino acids 1-24 of the Human ACTH conjugated to Keyhole Limpet Haemocyanin.AA Sequence:SYSMEHFRWGKPVGKKRRPVKVYPGeneID:5443
Application: ELISA.Immunohistochemistry on Formalin Fixed Paraffin Embedded Sections: 1/100-1/200 (Requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase).
Background: ACTH, released from the anterior pituitary gland in response to corticotropin-releasing hormone from the hypothalamus, acts on the adrenal cortex to stimulate the production of corticosteroids such as cortisol, involved in the response to stress. Studies
Concentration: 1.0 mg/ml
Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: PBS, pH 7.2
Preservatives: 0.09% Sodium Azide
State: Liquid purified IgG fractionAff – Purified
Specifictiy: This antibody recognizes 1-24 ACTH (Synacthen) which, as a synthetic analogue of naturally-occurring Adrenocorticotropic Hormone, can be used to measure adrenal reserve and for the diagnosis of adrenal insufficiency by acute adrenocortical stimulation.It
