Product: AM20226PU-S8-Hydroxy-Guanosine / 8-OHG antibody
Quantity: 20 µg
Synonyms: 8-Hydroxy-2-deoxyguanosine, 8-Hydroxyguanine, 8-Hydroxyguanosine, 8-OFdG, 8-OHG, 8OG, 8OHG, 8OHdG
Presentation: Purified
Clonality: Monoclonal
Host: Mouse
Isotype: IgG1
CAS NO: 1989-52-2 Product: Cholesterol myristate
Shipping to: Worldwide
Immunogen: 8-OHdG conjugated Keyhole Limpet Hemocyanin
Application: ELISA (Ref.3).Immunohistochemistry on Paraffin Sections: 3-5 µg/ml (See Ref.1-6 for more details). Immunocytochemistry (Ref.7).
Background: 8 Hydroxyguanosine (80G) is a modified base which occurs in DNA as a result of oxidative stress. 8 Hydroxy-2deoxyguanosine (8OHdG) has become a sensitive marker of oxidative damage in cellular DNA and has been reported to be excreted in the urine. Levels
Concentration:
Storage: Store lyophilized at 2-8°C for 6 months or at -20°C long term.After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System:
Preservatives:
State: Lyophilized purified AscitesPurified
Specifictiy: Recognizes 8-OHdG.19 analogues of 8-OHdG {guanosine (G), 7-methyl-G, 6-SH-G, 8-bromo-G, dA, dC, dT, dI, dU, dG, O6-methyl-dG, 8-OHdA, guanine (Gua), O6-methyl-Gua, 8-OHGua, uric acid, Urea, creatine, creatinine} demonstrate no cross-reactivity.Only 8-sulf
