Product: AM26229PU-NARHGEF2 antibody
Quantity: 0.1 mg
Synonyms: GEF-H1, Guanine nucleotide exchange factor H1, KIAA0651, LFP40, Microtubule-regulated Rho-GEF, Proliferating cell nucleolar antigen p40, Rho guanine nucleotide exchange factor 2
Presentation: Purified
Clonality: Monoclonal
Host: Mouse
Isotype: IgG1
CAS NO: 878739-06-1 Product: AZ 628
Shipping to: Worldwide
Immunogen:
Application: Immunohistochemstry on frozen sections (1): Cells were either fixed with methanol at -20 °C or with 3% PFA followed by permeabilization with Triton X-100. The typical starting working dilution is 1:50. Immunoflourescence (1-4).Immunprecipitation (1-3).Wes
Background: GEFH1 is an ~110 kDa protein belonging to the Dbl family of proto-oncogenes. GEF-H1 can activate the small GTPase RhoA, but not Rac1 or Cdc42. Rho family GTPases are central regulators of epithelial tight junctions and the cytoskeleton. GEF-H1 can associa
Concentration: 0.1 mg/ml
Storage: Store at 2 – 8 °C. Shelf life: one year from despatch.
Buffer System: PBS
Preservatives: 0.02% sodium azide
State: Liquid 0.2 µm filtered Ig fractionPurified
Specifictiy: The monoclonal antibody B4/7 recognizes guanine nucleotide exchange factor H1 (GEF-H1).
