Product: AM32024SU-NABCC2 / CMOAT / MRP2 antibody
Quantity: 1 ml
Synonyms: ATP-binding cassette sub-family C member 2, CMOAT1, CMRP, Canalicular multidrug resistance protein, Canalicular multispecific organic anion transporter 1, Multidrug resistance-associated protein 2
Presentation: Supernatant
Clonality: Monoclonal
Host: Mouse
Isotype: IgG2b
CAS NO: 578-74-5 Product: Apigenin 7-glucoside
Shipping to: Worldwide
Immunogen: A fusion protein of the bacterial maltose binding protein and Rat Mrp2, containing the 202-amino acid COOH terminal end of the transporter protein.GeneID:1244
Application: Western blotting: Use at 1/20-50 and anti-Mouse-HRP. Flow Cytometry: Optimal conditions still to be defined. Immunocytochemistry: Use at 1/20-50 on Acetone Fixed Cytospin preparations. Immunohistochemistry on Frozen Sections: 1/20 on Acetone Fixed Froze
Background: MRP2 is a 190-200 kD transmembrane protein earlier known as the canalicular multi-organic anion transporter cMOAT, absent in patients with the Dubin-Johnson syndrome, an autosomal recessive liver disorder characterized by chronic conjugated hyperbilirubin
Concentration: 0.25 mg/ml IgG (by ELISA)
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System:
Preservatives: 0.09% Sodium Azide
State: Serum Free Culture Supernatant (1 ml >> 200 Tests)Supernatant
Specifictiy: This Monoclonal antibody clone M2III-5 reacts with an internal epitope of MRP2. The Mab detects Rat, Mouse and Human MRP2. M2III-5 does not cross-react with the Human MDR1 P-gp, MRP1, MRP3 orMRP5 gene products.
