Product: AM32053SU-NABCC1 / MRP1 antibody
Quantity: 1 ml
Synonyms: ATP-binding cassette sub-family C member 1, LTC4 transporter, Multidrug resistance-associated protein 1
Presentation: Supernatant
Clonality: Monoclonal
Host: Rat
Isotype: IgG2a
CAS NO: 1884712-47-3 Product: CPI-637
Shipping to: Worldwide
Immunogen: Bacterial fusion protein of MRP, containing a segment of 168 amino acids (aa 192-360) in the amino-proximal half of the protein.GeneID:4363
Application: Flow Cytometry: Use at least 1/20-1/50. Cell permeabilization required with 10% lyzing solution followed by primairy antibody and anti-Rat-FITC. Western blotting: Use at least 1/20-1/50. Use an anti-Rat HRP. Immunocytochemistry: Use at least 1/20-1/50 on
Background: MRP1 (also known as ABCC, GS-X, ABC29) functions as a multispecific organic anion transporter, with (oxidized) glutathione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates
Concentration: approx. 250 µg Ig /ml
Storage: Store the antibody undiluted at 2-8°C for 3 months or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Buffer System:
Preservatives: 0.09% Sodium Azide
State: Serum-Free Tissue Culture SupernatantSupernatant
Specifictiy: This Monoclonal antibody MRPr1 reacts with an epitope of MRP, a 180-195 kD transmembrane transporter protein overexpressed in various Human non-P-glycoprotein MDR tumor cell lines. It does not cross-react with the Human MDR1 and MDR3 gene products (See Fl
