Product: AM32054SU-NABCC1 / MRP1 antibody
Quantity: 1 ml
Synonyms: ATP-binding cassette sub-family C member 1, LTC4 transporter, Multidrug resistance-associated protein 1
Presentation: Supernatant
Clonality: Monoclonal
Host: Mouse
Isotype: IgG1
CAS NO: 1642300-52-4 Product: KPT-8602
Shipping to: Worldwide
Immunogen: Bacterial fusion protein of MRP, containing a segment of 170 amino acids in the carboxy terminal end and part of the carboxy proximal nucleotide binding domain of the protein.GeneID:4363
Application: Flow Cytometry: 1/20-1/50. Cell permeabilization required with 10% lyzing solution followed by primairy antibody and anti-Mouse-FITC. Western blotting: 1/20-1/50.Immunocytochemistry on Aceton-Fixed Cell Preparation: 1/20-1/50.Immunohistochemstry on Aceton
Background: MRP1 (also known as ABCC, GS-X, ABC29) functions as a multispecific organic anion transporter, with (oxidized) glutathione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates
Concentration: ~ 250 µg Ig/ml
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System:
Preservatives: 0.09% Sodium Azide
State: Serum-Free Tissue Culture SupernatantSupernatant
Specifictiy: This Monoclonal antibody MRPm6 reacts with an internal epitope of MRP, a 180-195 kD transmembrane transporter protein overexpressed in various Human non-P-glycoprotein MDR tumor cell lines. MRPm6 does not cross react with the Human MDR1 and MDR3 gene prod