Product: AP05274PU-NAKT1 / PKB pThr308 antibody
Quantity: 10 Blots
Synonyms: Akt-1, C-AKT, Protein kinase B, RAC-PK-alpha, RAC-alpha serine/threonine-protein kinase
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
CAS NO: 466-24-0 Product: Benzoylaconine
Shipping to: Worldwide
Immunogen: Chemically synthesized phosphopeptide derived from the region of human Akt1 that contains threonine 308.GeneID:207Remarks:The sequence is conserved among multiple species including mouse and rat Akt1 and Akt2.
Application: Western blot: (1:1000 starting dilution).Positive control: 3T3-L1 pre-adipocytes +/- PDGF treatment; HEK293 cells coexperessing RasV12 and RacL61.
Background: Akt, also known as Protein Kinase B (PKB) or RAC- , is a 60 kDa serine/threonine kinase that plays an important role in multiple biological responses including metabolism, cell survival and growth by phosphorylating many proteins including GSK-3 , caspase
Concentration: Lot specific
Storage: Store the product (in aliquots) at -20 °C. Can be shipped at 2 – 8 °C.Avoid repeated freezing and thawing.Shelf life: One year from despatch.
Buffer System: Phosphate buffered saline, pH 7.3, with 1.0 mg/ml BSA 0.05% sodium azide and 50% glycerol
Preservatives:
State: Liquid Ig fractionAff – Purified
Specifictiy: This antibody detects Akt/PKB pThr308.
