Product: AP05812PU-SAPAF1 antibody
Quantity: 50 µg
Synonyms: Apaf-1, Apoptotic protease-activating factor 1, KIAA0413
Presentation: Purified
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
CAS NO: 3520-43-2 Product: JC-1
Shipping to: Worldwide
Immunogen: Synthetic peptide corresponding to amino acids 12-28 of Human Apaf1GeneID:317
Application: Western blot: 1/1000-1/2000. Immunohistochemistry on Paraffin Sections: Requires antigen retrieval using heat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 is recommended for this purpose.
Background: Apaf1 (Apoptosis protease activating factor 1) is the mammalian homologue of the CED-4 cell death protein in C. Elegans. Apaf1 binds to cytochrome C and caspase-9 leading to caspase-9 activation, resulting in the beginning of the proteolytic cascade chara
Concentration: 0.5 mg/ml
Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: PBS
Preservatives: 0.02% Sodium Azide
State: Liquid purified IgG fractionPurified
Specifictiy: This antibody recognises a 130kD band in Western blots.