Product: AP08252PU-NAIRE / APECED (C-term) antibody
Quantity: 50 µg
Synonyms: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, Autoimmune regulator
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Goat
Isotype: IgG
CAS NO: 6809-52-5 Product: Teprenone
Shipping to: Worldwide
Immunogen: Synthetic peptide corresponding to the C-Terminal of Human AIRE (NP_000374.1, NP_000649.1)AA Sequence:C-QSMARPAAPFPSGeneID:326Remarks:Percent identity by BLAST analysis: Human, Gorilla (100%)
Application: Immunohistochemistry on Paraffin Sections: 2.5 µg/ml (Heat induced antigen retrieval is required).Radioimmunoassay (RIA): 0.01-0.03 µg/ml.ELISA: 1/32000.
Background: AIRE is a transcriptional regulator that is thought to be important in controlling tissue-specific expression of genes in the thymus. The precise function of the protein is not well defined. It contains zinc finger motifs and isoform 1 is localized to bot
Concentration: 0.5 mg/ml
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Preservatives:
State: Liquid purified Ig fractionAff – Purified
Specifictiy: This antibody recognize two of the tree reported isoforms (NP_000374.1 and NP_000649.1) from the C-terminus of human AIRE.
