Product: AP08974PU-NAKR1C4 (2-14) antibody
Quantity: 50 µg
Synonyms: 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, Aldo-keto reductase family 1 member C4, CDR, CHDR, Chlordecone reductase, DD-4, DD4, Dihydrodiol dehydrogenase 4, HAKRA
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Goat
Isotype:
CAS NO: 17008-69-4 Product: Pseudobufarenogin
Shipping to: Worldwide
Immunogen: Synthetic peptide from N-terminus of human AKR1C4AA Sequence:DPKYQRVELNDGH-CGeneID:1109Remarks:Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Bovine (92%); Marmoset, Horse (85%)
Application: Immunohistochemistry on paraffin sections: 2.5 µg/ml (heat induced antigen retrieval in pH 6.0 citrate buffer).Western blot: 0.1 – 0.3 µg/ml.ELISA: 1/4000.
Background: HSD3a catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3alpha,17beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity.
Concentration: 1.0 mg/ml
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
Preservatives:
State: Liquid purified IgAff – Purified
Specifictiy: This antibody reacts to Chlordecone Reductase (AKR1C4) at aa 2-14.
