Product: AP22390PU-NALDH5A1 / SSADH (485-496) antibody
Quantity: 0.1 mg
Synonyms: Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, Succinate-semialdehyde dehydrogenase, mitochondrial
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Goat
Isotype:
CAS NO: 891025-25-5 Product: BAMB-4
Shipping to: Worldwide
Immunogen: Peptide with sequence from the internal region of Human ALDH5A1.AA Sequence:C-SQDPAQIWRVAEGeneID:7915Remarks:Amino acid numbering in name calculated from NP_733936.1.
Application: Peptide ELISA: 1/32000 (Detection Limit). Western blot: 0.3-1 µg/ml. This antibody detects a band of Approx 55kDa in Human Liver lysates and 50kDa band in Mouse and Rat Liver lysates.Immunohistochemistry on Paraffin Sections: 5-10 µg/ml. In paraffin embed
Background: Defects in ALDH5A1 are the cause of succinate semialdehyde dehydrogenase deficiency (SSADH deficiency) [MIM:271980]. SSADH deficiency is a rare inborn error in the metabolism of 4-aminobutyric acid (GABA) which leads to accumulation of 4-hydroxybutyric ac
Concentration: 0.5 mg/ml
Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: Tris saline, pH~7.3
Preservatives: 0.02% Sodium Azide
State: Liquid purified Ig fractionAff – Purified
Specifictiy: This antibody is expected to recognize both reported isoforms (NP_733936.1; NP_001071.1).
