Product: AP23022PU-NAPEX1 / REF-1 (2-15) antibody
Quantity: 50 µg
Synonyms: APE, APEN, APEX, APEX nuclease, APX, Apurinic-apyrimidinic endonuclease 1, HAP1, Protein REF-1, REF1
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Goat
Isotype:
CAS NO: 195371-52-9 Product: NSC 42834
Shipping to: Worldwide
Immunogen: Synthetic peptide from N Terminus of APE1 / APEX1 – KLH conjugatedAA Sequence:PKRGKKGAVAEDGDGeneID:328Remarks:Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (100%); Marmoset, Panda, Bat, Horse, Pig (93%); Rabbit
Application: Western blot (0.2 – 1 µg/ml).ELISA.Immunohistochemistry on paraffin sections (5 µg/ml).
Background: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so
Concentration: 0.5 mg/ml
Storage: Store at 2 – 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
Preservatives:
State: Liquid Ig fractionAff – Purified
Specifictiy: This antibody detects APEX1 / REF-1 (N-term).
