Product: DM378ABCC7 / CFTR antibody
Quantity: 1 ml
Synonyms: ATP-binding cassette transporter sub-family C member 7, Channel conductance-controlling ATPase, Cystic fibrosis transmembrane conductance regulator, cAMP-dependent chloride channel
Presentation: Purified
Clonality: Monoclonal
Host: Mouse
Isotype: IgG1
CAS NO: 17650-98-5 Product: Ceruletide
Shipping to: Worldwide
Immunogen: BALB/C mice were immunized with recombinant protein encoding NBF2 domain of human CFTR.GeneID:1080
Application: Immunohistochemistry on Paraffin Embedded Sections: Use a dilution of 1/50-1/100 in an ABC method (30 minutes at room temperature).Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.
Background: Cystic Fibrosis Transmembrane Regulator (CFTR) is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD) and one R domain. It is structurally similar to multidrug resistance protein (Mdr1). CFTR is found in the apical membra
Concentration:
Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System:
Preservatives: < 0.1% Sodium Azide
State: Liquid ascitesPurified
Specifictiy: This antibody detects ABCC7/CFTRIt reacts with a protein of 165-170 kD.Cellular Localization: Cell membrane
