Product: TA302643APEX1 / REF-1 (N-term) antibody
Quantity: 0.1 mg
Synonyms: APE, APEN, APEX, APEX nuclease, APX, Apurinic-apyrimidinic endonuclease 1, HAP1, Protein REF-1, REF1
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Goat
Isotype:
CAS NO: 172732-68-2 Product: Varespladib
Shipping to: Europe, USA/Canada
Immunogen: Synthetic peptide from the N-Terminus of Human APEX1 / APE1 (NP_001632.2).AA Sequence:PKRGKKGAVAEDGD-CGeneID:328Remarks:Reported variants represent identical protein (NP_001632.2; NP_542379.1; NP_542380.1).
Application: Peptide ELISA: 1/16000 (Detection Limit).Western blot: 0.1-0.3 µg/ml. Approx 35-37 kDa band observed in Human lysates of cell lines A431 and HeLa. Immunohistochemistry on Paraffin Sections: 4-6 µg/ml. In paraffin embedded Human Breast shows nuclear staini
Background: Apurinic / apyrimidinic endonuclease (APE1 or REF1) is responsible for the incision of DNA basic sites during base excision repair. It has also been shown to stimulate the DNA binding activity of numerous transcription factors that are involved in cancer
Concentration: 0.5 mg/ml
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: Tris saline, pH~7.3
Preservatives: 0.02% Sodium Azide
State: Liquid purified Ig fractionAff – Purified
Specifictiy: This antibody detects APEX1 / REF-1 at N-term.
