Product: TA341187ADAMTS5 (N-term) antibody
Quantity: 50 µg
Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 5, ADAM-TS5, ADAMTS-5, ADAMTS11, ADMP-2, ADMP2, Aggrecanase-2
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
CAS NO: 81025-04-9 Product: Lactitol (monohydrate)
Shipping to: Europe, USA/Canada
Immunogen: Synthetic 20 amino acid peptide from N-terminus of human ADAMTS5GeneID:11096Remarks:Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset (95%); Panda, Pig (85%); Rat, Bovine (80%)
Application: Immunohistochemistry on Paraffin Embedded Tissues: 14 µg/ml (after heat induced antigen retrieval in pH 6.0 citrate buffer).
Background: ADAMTS5, also known as aggrecanase-2, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan. The protein contains a signal sequence, a prodomain with both a potential cysteine switch and a
Concentration: 1.0 mg/ml
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: PBS containing 0.09% Sodium Azide as preservative
Preservatives:
State: Liquid purified Ig fractionAff – Purified
Specifictiy: This antibody reacts N-terminal domain of human ADAMTS5.BLAST analysis of the peptide immunogen showed no homology with other human proteins.
