Product: TA341194ADAMTS4 (C-term) antibody
Quantity: 50 µg
Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS4, ADAMTS-4, ADMP-1, ADMP1, Aggrecanase-1, KIAA0688
Presentation: Aff – Purified
Clonality: Polyclonal
Host: Rabbit
Isotype: IgG
CAS NO: 553-12-8 Product: Protoporphyrin IX
Shipping to: Europe, USA/Canada
Immunogen: Synthetic 17 amino acid peptide from C-terminus of human ADAMTS4GeneID:9507Remarks:Percent identity with other species by BLAST analysis: Human, Orangutan, Gibbon, Dog, Horse (100%); Marmoset, Bat, Bovine, Elephant, Panda (94%); Monkey, Pig, Opossum (88%)
Application: Immunohistochemistry on Paraffin Embedded Tissues: 20 µg/ml (after heat induced antigen retrieval in pH 6.0 citrate buffer).
Background: ADAMTS4, also known as aggrecanase-1, is a Metallopeptidase M12B type protease that is responsible for degradation of the articular cartilage protein aggrecan and the brain extracellular matrix proteoglycan brevican. The ADAMTS4 protein contains a signal
Concentration: 1.0 mg/ml
Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.Avoid repeated freezing and thawing.Shelf life: one year from despatch.
Buffer System: PBS containing 0.09% Sodium Azide as preservative
Preservatives:
State: Liquid purified Ig fractionAff – Purified
Specifictiy: This antibody reacts with C-terminal domain of human ADAMTS4.BLAST analysis of the peptide immunogen showed no homology with other human proteins.