Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This article is distributed beneath the terms of your Inventive Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution with the function with out additional permission offered the original work is attributed as specified around the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).two water content, volume, or frequency of stools.11 A decrease in consistency (ie, soft or liquid) and a rise inside the frequency of bowel movements to three stools every day have frequently been employed as a definition for epidemiological investigations. Depending on a community-based study perspective, diarrhea is defined as at the very least 3 or far more loose stools inside a 24-hour period.12 A diarrheal episode is regarded as because the passage of three or additional loose or liquid stools in 24 hours prior to presentation for care, which is regarded the most practicable in kids and adults.13 Even so, prolonged and persistent diarrhea can last amongst 7 and 13 days and no less than 14 days, respectively.14,15 The disease is extremely sensitive to climate, showing seasonal variations in quite a few sites.16 The climate sensitivity of diarrheal illness is consistent with observations on the direct effects of climate variables on the causative AH252723 cost agents. Temperature and relative humidity have a direct influence around the price of replication of bacterial and protozoan pathogens and around the survival of enteroviruses in the environment.17 Health care journal.pone.0169185 seeking is recognized to be a outcome of a complicated behavioral course of action that is certainly influenced by several components, including socioeconomic and TER199 web demographic and characteristics, perceived require, accessibility, and service availability.Diseases constituted 9 of all deaths among children <5 years old in 2015.4 Although the burden of diarrheal diseases is much lower in developed countries, it is an important public health problem in low- and middle-income countries because the disease is particularly dangerous for young children, who are more susceptible to dehydration and nutritional losses in those settings.5 In Bangladesh, the burden of diarrheal diseases is significant among children <5 years old.6 Global estimates of the mortality resulting from diarrhea have shown a steady decline since the 1980s. However, despite all advances in health technology, improved management, and increased use of oral rehydrationtherapy, diarrheal diseases are also still a leading cause of public health concern.7 Moreover, morbidity caused by diarrhea has not declined as rapidly as mortality, and global estimates remain at between 2 and 3 episodes of diarrhea annually for children <5 years old.8 There are several studies assessing the prevalence of childhood diarrhea in children <5 years of age. However, in Bangladesh, information on the age-specific prevalence rate of childhood diarrhea is still limited, although such studies are vital for informing policies and allowing international comparisons.9,10 Clinically speaking, diarrhea is an alteration in a normal bowel movement characterized by an increase in theInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh 2 University of Strathclyde, Glasgow, UK Corresponding Author: Abdur Razzaque Sarker, Health Economics and Financing Research, International Centre for Diarrhoeal Disease Research, 68, Shaheed Tajuddin Sarani, Dhaka 1212, Bangladesh. Email: [email protected] Commons Non Commercial CC-BY-NC: a0023781 This short article is distributed beneath the terms of your Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits noncommercial use, reproduction and distribution with the operate without the need of further permission provided the original perform is attributed as specified around the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).2 water content material, volume, or frequency of stools.11 A decrease in consistency (ie, soft or liquid) and a rise inside the frequency of bowel movements to 3 stools each day have typically been employed as a definition for epidemiological investigations. Depending on a community-based study perspective, diarrhea is defined as at least 3 or extra loose stools within a 24-hour period.12 A diarrheal episode is considered as the passage of 3 or far more loose or liquid stools in 24 hours prior to presentation for care, which can be considered the most practicable in youngsters and adults.13 Nonetheless, prolonged and persistent diarrhea can last amongst 7 and 13 days and a minimum of 14 days, respectively.14,15 The disease is very sensitive to climate, displaying seasonal variations in many internet sites.16 The climate sensitivity of diarrheal disease is consistent with observations on the direct effects of climate variables on the causative agents. Temperature and relative humidity possess a direct influence around the rate of replication of bacterial and protozoan pathogens and on the survival of enteroviruses in the environment.17 Overall health care journal.pone.0169185 looking for is recognized to become a result of a complicated behavioral approach that is influenced by many factors, like socioeconomic and demographic and qualities, perceived need, accessibility, and service availability.