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ELAVL1 regulates choice splicing of eIF4E transporter to market postnatal angiogenesisSung-Hee Changa,1, Olivier Elementob, Jiasheng Zhangc, Zhen W. Zhuangc, Michael Simonsc, and Timothy Hlaa,a middle for Vascular Biology, Division of Pathology and Laboratory Medicine, and bInstitute for Computational Biomedicine, Department of Physiology and Biophysics, Weill Cornell Health care College, Cornell University, New york, NY 10065; and cYale Cardiovascular Investigation Heart, Yale College College of drugs, New Haven, CTEdited by Napoleone Ferrara, College of California, San Diego, La Jolla, CA, and accredited Oct 28, 2014 (received for assessment June 27, 2014)Posttranscriptional RNA regulation is crucial in deciding the plasticity of mobile phenotypes. Nevertheless, mechanisms of how RNA binding proteins (RBPs) influence mobile actions are badly recognized. We clearly show here which the RBP embryonic lethal irregular eyesight like one (ELAVL1, also know as HuR) regulates the choice splicing of eukaryotic tran.
