Name :
Recombinant Human CD44 Protein, hFc-tagged, FITC conjugated
Specification :
| Description : CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types. CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 function is controlled by its posttranslational modifications. One critical modification involves discrete sialofucosylations rendering the selectin-binding glycoform of CD44 called HCELL (for Hematopoietic Cell E-selectin/L-selectin Ligand). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms. | Source : HEK293 | Species : Human | Tag : hFc | Form : Lyophilized | Molecular Mass : This protein has a calculated MW of 48.7 kDa. The reducing (R) protein migrates as 76 kDa in SDS-PAGE due to glycosylation. | Protein length : Gln21-Pro220 | N-terminal Sequence Analysis : Gln 21 | Endotoxin : | Purity : > 95 % as determined by SDS-PAGE | Characteristic : Disulfide-linked homodimerLabeled with FITC via aminesExcitation source: 488 nm spectral line, argon-ion laserExcitation Wavelength: 488 nmEmission Wavelength: 535 nm | Storage : For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.Please avoid repeated freeze-thaw cycles.This product is stable after storage at:-20 to -70 centigrade for 12 months in lyophilized state;-70 centigrade for 3 months under sterile conditions after reconstitution. | Storage Buffer : Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5, 10% trehalose. | Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.
Gene Information :
| Gene Name : CD44 | Official Symbol : CD44 | Synonyms : CD44; CD44 molecule (Indian blood group); CD44 antigen (homing function and Indian blood group system) , MDU2, MDU3, MIC4; CD44 antigen; CD44R; chondroitin sulfate proteoglycan 8; CSPG8; HCELL; hematopoietic cell E and L selectin ligand; IN; MC56; Pgp1; epican; Hermes antigen; hyaluronate receptor; phagocytic glycoprotein 1; heparan sulfate proteoglycan; cell surface glycoprotein CD44; extracellular matrix receptor III; GP90 lymphocyte homing/adhesion receptor; hematopoietic cell E- and L-selectin ligand; homing function and Indian blood group system; LHR; MDU2; MDU3; MIC4; CDW44; HUTCH-I; ECMR-III; MGC10468 | Gene ID : 960 | mRNA Refseq : NM_000610 | Protein Refseq : NP_000601 | MIM : 107269 | UniProt ID : P16070
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