Recombinant Human CD44 Protein, His and Strep-tagged

Specification :
| Description : The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. | Source : HEK293 | Species : Human | Tag : His and Strep | Form : Lyophilized | Molecular Mass : 22.9 kDa | Protein Length : 742 | AA Sequence : MDKFWWHAAWGLCLVPLSLAQIDLN ITCRFAGVFHVEKNGRYSISRTEAA DLCKAFNSTLPTMAQMEKALSIGFE TCRYGFIEGHVVIPRIHPNSICAAN NTGVYILTSNTSQYDTYCFNASAPP EEDCTSVTDLPNAFDGPITITIVNR DGTRYVQKGEYRTNPEDIYPSNPTD DDVSSGSSSERSSTSGGYIFYTFST VHPIPDEDSPWITDSTDRIPATTLM STSATATETATKRQETWDWFSWLFL PSESKNHLHTTTQMAGTSSNTISAG WEPNEENEDERDRHLSFSGSGIDDD EDFISSTISTTPRAFDHTKQNQDWT QWNPSHSNPEVLLQTTTRMTDVDRN GTTAYEGNWNPEAHPPLIHHEHHEE EETPHSTSTIQATPSSTTEETATQK EQWFGNRWHEGYRQTPKEDSHSTTG TAAASAHTSHPMQGRTTPSPEDSSW TDFFNPISHPMGRGHQAGRRMDMDS SHSITLQPTANPNTGLVEDLDRTGP LSMTTQQSNSQSFSTSHEGLEEDKD HPTTSTLTSSNRNDVTGGRRDPNHS EGSTTLLEGYTSHYPHTKESRTFIP VTSAKTGSFGVTAVTVGDSNSNVNR SLSGDQDTFHPSGGSHTTHGSESDG HSHGSQEGGANTTSGPIRTPQIPEW LIILASLLALALILAVCIAVNSRRR CGQKKKLVINSGNGAVEDRKPSGLN GEASKSQEMVHLVNKESSETPDQFM TADETRNLQNVDMKIGV | Purity : > 98% | Applications : WB; ELISA; FACS; FC | Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. | Storage : At -20 centigrade. | Concentration : 1 mg/mL | Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution. | Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.