Active Recombinant Human CDH2, Fc tagged

Specification :
| Description : This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. | Source : Mammalian cells | Species : Human | Tag : Fc | Predicted N Terminal : Asp160 | Form : Lyophilized from a 0.2 µm filtered solution in Tris-Citrate. See Certificate of Analysis for details. | Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of U-118-MG human glioblastoma/astrocytoma cells.When 5 x 10^4 cells/well are added to Recombinant Human N-Cadherin Fc Chimera coated plates (10 µg/mL, 100 µL/well), =55% will adhere after 1 hour at room temperature. | Molecular Mass : Predicted Molecular Mass:89.2 kDa (monomer);SDS-PAGE:115 – 130 kDa, reducing conditions | Endotoxin : | Purity : >90%, by SDS-PAGE under reducing conditions and visualized by silver stain. | Stability : Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution. | Shipping : Reconstitute at 100 µg/mL in sterile, deionized water containing 2 mM calcium 24 hours prior to use.