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Name :
Recombinant Human CD63 Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 25.6 kDa | AA Sequence : MAVEGGMKCVKFLLYVLLLAFCACA VGLIAVGVGAQLVLSQTIIQGATPG SLLPVVIIAVGVFLFLVAFVGCCGA CKENYCLMITFAIFLSLIMLVEVAA AIAGYVFRDKVMSEFNNNFRQQMEN YPKNNHTASILDRMQADFKCCGAAN YTDWEKIPSMSKNRVPDSCCINVTV GCGINFNEKAIHKEGCVEKIGGWLR KNVLVVAAAALGIAFVEVLGIVFAC CLVKSIRSGYEVMTRTRPLEQKLIS EEDLAANDILDYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information :
| Gene Name : CD63 CD63 molecule [ Homo sapiens (human) ] | Official Symbol : CD63 | Synonyms : CD63; CD63 molecule; CD63 antigen (melanoma 1 antigen), MLA1; CD63 antigen; ME491; TSPAN30; tspan-30; granulophysin; tetraspanin-30; melanoma-associated antigen MLA1; CD63 antigen (melanoma 1 antigen); melanoma-associated antigen ME491; ocular melanoma-associated antigen; lysosomal-associated membrane protein 3; lysosome-associated membrane glycoprotein 3; MLA1; LAMP-3; OMA81H; | Gene ID : 967 | mRNA Refseq : NM_001780 | Protein Refseq : NP_001771 | MIM : 155740 | UniProt ID : P08962

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors