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Name :
Recombinant Human CD70 Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 21.1 kDa | AA Sequence : MPEEGSGCSVRRRPYGCVLRAALVP LVAGLVICLVVCIQRFAQAQQQLPL ESLGWDVAELQLNHTGPQQDPRLYW QGGPALGRSFLHGPELDKGQLRIHR DGIYMVHIQVTLAICSSTTASRHHP TTLAVGICSPASRSISLLRLSFHQG CTIASQRLTPLARGDTLCTNLTGTL LPSRNTDETFFGVQWVRPTRTRPLE QKLISEEDLAANDILDYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information :
| Gene Name : CD70 CD70 molecule [ Homo sapiens (human) ] | Official Symbol : CD70 | Synonyms : CD70; CD70 molecule; CD27LG, TNFSF7, tumor necrosis factor (ligand) superfamily, member 7; CD70 antigen; CD27L; CD27-L; CD27 ligand; Ki-24 antigen; surface antigen CD70; tumor necrosis factor ligand superfamily member 7; tumor necrosis factor (ligand) superfamily, member 7; CD27LG; TNFSF7; | Gene ID : 970 | mRNA Refseq : NM_001252 | Protein Refseq : NP_001243 | MIM : 602840 | UniProt ID : P32970

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors