Recombinant Human CD74, GST-Tagged

Specification :
| Cat. No. : CD74-2230H | Description : The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. | Sequence : MHRRRSRSCREDQKPVMDDQRDLIS NNEQLPMLGRRPGAPESKCSRGALY TGFSILVTLLLAGQATTAYFLYQQQ GRLDKLTVTSQNLQLENLRMKLPKP PKPVSKMRMATPLLMQALPMGALPQ GPMQNATKYGNMTEDHVMHLLQSHW NWRTRLLGWV | MW (kDa) : 43.34 | Preparation Method : in vitro wheat germ expression system | Purification : Glutathione Sepharose 4 Fast Flow | Applications : Antibody Production; Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Protein Array | Storage : Store at -80°C. Aliquot to avoid repeated freezing and thawing.