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Name :
Recombinant Human CD80 Protein, His-Flag-StrepII-Tagged

Specification :
| Description : The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011] | Source : Human cells | Species : Human | Tag : His-Flag-StrepII | Form : Liquid | Bio-activity : Not Tested | Molecular Mass : 28.16 kDa | AA Sequence : VIHVTKEVKEVATLSCGHNVSVEEL AQTRIYWQKEKKMVLTMMSGDMNIW PEYKNRTIFDITNNLSIVILALRPS DEGTYECVVLKYEKDAFKREHLAEV TLSVKADFPTPSISDFEIPTSNIRR IICSTSGGFPEPHLSWLENGEELNA INTTVSQDPETELYAVSSKLDFNMT TNHSFMCLIKYGHLRVNQTFNWNTT KQEHFPDN | Applications : Western BlotEnzyme-linked Immunoabsorbent AssaySDS-PAGEProtein Interaction | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Concentration : ≥ 10 μg/mL | Storage Buffer : 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.

Gene Information :
| Gene Name : CD80 CD80 molecule [ Homo sapiens ] | Official Symbol : CD80 | Synonyms : CD80; CD80 molecule; CD28LG, CD28LG1, CD80 antigen (CD28 antigen ligand 1, B7 1 antigen), CD80 molecule; T-lymphocyte activation antigen CD80; B lymphocyte activation antigen B7; B7 1; B7.1; activation B7-1 antigen; costimulatory factor CD80; CTLA-4 counter-receptor B7.1; B-lymphocyte activation antigen B7; costimulatory molecule variant IgV-CD80; CD80 antigen (CD28 antigen ligand 1, B7-1 antigen); B7; BB1; B7-1; LAB7; CD28LG; CD28LG1; | Gene ID : 941 | mRNA Refseq : NM_005191 | Protein Refseq : NP_005182 | MIM : 112203 | UniProt ID : P33681

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors