Recombinant Human CD80 Protein, His-tagged

Specification :
| Description : CD80, also known as T-lymphocyte activation antigen CD80, is a member of cell surface immunoglobulin superfamily. This protein can bind to either human or mouse CD28 and CTLA-4. It is expressed on activated B cells, activated T cells, and macrophages. The B7/CD28/CTLA4 pathway has the ability to both positively and negatively regulate immune responses. Therefore, it is considered a promising therapeutic target for autoimmune diseases and various carcinomas. | Source : Insect cells | Species : Human | Tag : His | Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. | Molecular Mass : 24.9kDa (216aa) 28-40kDa (SDS-PAGE under reducing conditions) | Protein length : 35-242aa | AA Sequence : VIHVTKEVKE VATLSCGHNV SVEELAQTRI YWQKEKKMVL TMMSGDMNIW PEYKNRTIFD ITNNLSIVIL ALRPSDEGTY ECVVLKYEKDAFKREHLAEV TLSVKADFPT PSISDFEIPT SNIRRIICST SGGFPEPHLS WLENGEELNA INTTVSQDPE TELYAVSSKL DFNMTTNHSFMCLIKYGHLR VNQTFNWNTT KQEHFPDNLE HHHHHH | Purity : > 95% by SDS – PAGE | Applications : SDS-PAGE | Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. | Concentration : 0.5mg/ml (determined by Absorbance at 280nm)