Name :
Recombinant Human CD81 Protein, hIgG-His-tagged
Specification :
| Description : CD81, also known as CD81 antigen isoform 1, belongs to the tetraspanin family. It interacts directly with immunoglobulin superfamily member 8 (IGSF8, CD316) and CD36. In B cells, it is part of a complex with CD21, CD19 and Leu13. This complex reduces the threshold for B cell activation through B cell receptors by linking Ag specific recognition and CD21 mediator recognition. On T cells it associates with CD4 and CD8 and provides a costimulatory signal with CD3. | Source : Insect cells | Species : Human | Tag : hIgG-His | Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. | Molecular Mass : 37.0kDa (331aa) 40-57kDa (SDS-PAGE under reducing conditions) | Protein length : 113-201aa | AA Sequence : ADPFVNKDQI AKDVKQFYDQ ALQQAVVDDD ANNAKAVVKT FHETLDCCGS STLTALTTSV LKNNLCPSGS NIISNLFKED CHQKIDDLFSGKLEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRVVSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYKTTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H | Purity : > 95% by SDS – PAGE | Applications : SDS-PAGE | Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. | Concentration : 0.5mg/ml (determined by Absorbance at 280nm)
Gene Information :
| Gene Name : CD81 CD81 molecule [ Homo sapiens ] | Official Symbol : CD81 | Synonyms : CD81; CD81 molecule; CD81 antigen (target of antiproliferative 1) , TAPA1; CD81 antigen; TAPA 1; TSPAN28; tspan-28; tetraspanin-28; 26 kDa cell surface protein TAPA-1; CD81 antigen (target of antiproliferative 1); S5.7; CVID6; TAPA1; | Gene ID : 975 | mRNA Refseq : NM_004356 | Protein Refseq : NP_004347 | MIM : 186845 | UniProt ID : P60033
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