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Name :
Active Recombinant Human CLEC4M, Fc Chimera

Specification :
| Source : Mammalian cells | Species : Human | Tag : Fc Chimera | Predicted N Terminal : Met | Form : Lyophilized from a 0.2 µm filtered solution in Tris-Citrate. | Bio-activity : Measured by the ability of the immobilized protein to support the adhesion of ICAM-3 expressing CHO Chinese hamster ovary cells.When 5 x 10^4 cells/well are added to rhDC-SIGNR/Fc coated plates (5 µg/mL with 100 µL/well), approximately 40% – 70% of added cells will adhere after 1 hour at room temperature. Optimal dilutions should be determined by each laboratory for each application. | Molecular Mass : Recombinant Human CLEC4M, Fc Chimera has a calculated MW of 61.4 kDa (monomer). In SDS-PAGE migrates as 61-66 kDa, reducing conditions. | Purity : >80%, by SDS-PAGE under reducing conditions and visualized by silver stain. | Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information :
| Gene Name : CLEC4M C-type lectin domain family 4, member M [ Homo sapiens ] | Official Symbol : CLEC4M | Synonyms : CLEC4M; C-type lectin domain family 4, member M; CD209L, CD299, CD299 antigen; C-type lectin domain family 4 member M; DC SIGN2; DC SIGNR; DCSIGNR; HP10347; LSIGN; CD299 antigen; DC-SIGN-related protein; CD209 antigen-like protein 1; mannose binding C-type lectin DC-SIGNR; dendritic cell-specific ICAM-3-grabbing non-integrin 2; liver/lymph node-specific ICAM-3 grabbing non-integrin; liver/lymph node-specific ICAM-3-grabbing non-integrin; CD299; CD209L; L-SIGN; DC-SIGN2; DC-SIGNR; MGC47866; MGC129964; | Gene ID : 10332 | mRNA Refseq : NM_001144904 | Protein Refseq : NP_001138376 | MIM : 605872 | UniProt ID : Q9H2X3 | Chromosome Location : 19p13

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Author: Cholesterol Absorption Inhibitors