Recombinant Human CD86 Protein, DDK/His-tagged

Specification :
| Description : This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. | Source : HEK293 | Species : Human | Tag : DDK/His | Form : 1 x PBS, pH7.4, 10% glycerol. | Molecular Mass : 27 kDa | Protein length : Leu20 – Pro239 | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Concentration : >50 ug/mL as determined by microplate BCA method