Recombinant Human CD86 Protein, GST-Tagged

Specification :
| Description : This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 64.1 kDa | AA Sequence : MDPQCTMGLSNILFVMAFLLSGAAP LKIQAYFNETADLPCQFANSQNQSL SELVVFWQDQENLVLNEVYLGKEKF DSVHSKYMGRTSFDSDSWTLRLHNL QIKDKGLYQCIIHHKKPTGMIRIHQ MNSELSVLANFSQPEIVPISNITEN VYINLTCSSIHGYPEPKKMSVLLRT KNSTIEYDGIMQKSQDNVTELYDVS ISLSVSFPDVTSNMTIFCILETDKT RLLSSPFSIELEDPQPPPDHIPWIT AVLPTVIICVMVFCLILWKWKKKKR PRNSYKCGTNTMEREESEQTKKREK IHIPERSDETQRVFKSSKTSSCDKS DTCF | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.