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Name :
Recombinant Human CD86 Protein, GST-Tagged

Specification :
| Description : This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 64.1 kDa | AA Sequence : MDPQCTMGLSNILFVMAFLLSGAAP LKIQAYFNETADLPCQFANSQNQSL SELVVFWQDQENLVLNEVYLGKEKF DSVHSKYMGRTSFDSDSWTLRLHNL QIKDKGLYQCIIHHKKPTGMIRIHQ MNSELSVLANFSQPEIVPISNITEN VYINLTCSSIHGYPEPKKMSVLLRT KNSTIEYDGIMQKSQDNVTELYDVS ISLSVSFPDVTSNMTIFCILETDKT RLLSSPFSIELEDPQPPPDHIPWIT AVLPTVIICVMVFCLILWKWKKKKR PRNSYKCGTNTMEREESEQTKKREK IHIPERSDETQRVFKSSKTSSCDKS DTCF | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information :
| Gene Name : CD86 CD86 molecule [ Homo sapiens ] | Official Symbol : CD86 | Synonyms : CD86; CD86 molecule; CD28LG2, CD86 antigen (CD28 antigen ligand 2, B7 2 antigen); T-lymphocyte activation antigen CD86; B lymphocyte antigen B7 2; B7 2; B7.2; BU63; FUN-1; CTLA-4 counter-receptor B7.2; B-lymphocyte activation antigen B7-2; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); B70; B7-2; LAB72; CD28LG2; MGC34413; | Gene ID : 942 | mRNA Refseq : NM_001206924 | Protein Refseq : NP_001193853 | MIM : 601020 | UniProt ID : P42081

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Author: Cholesterol Absorption Inhibitors