Recombinant Human CD86 Protein (Leu26-Pro247), C-mFc and 6×His-tagged

Specification :
| Description : This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. | Source : HEK293 | Species : Human | Tag : C-mFc and 6×His | Form : Lyophilized | Molecular Mass : 52.4 kDa | Protein Length : Leu26-Pro247 | Purity : > 95% as determined by SDS-PAGE and Coomassie blue staining. | Storage : Store at -80 centigrade for 12 months (Avoid repeated freezing and thawing) | Storage Buffer : Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 41 % trehalose is added as protectants before lyophilization.