Active Recombinant Human CSF1R, Fc Chimera

Specification :
| Source : Mammalian cells | Species : Human | Tag : Fc Chimera | Predicted N Terminal : Ile20 | Form : Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein. | Bio-activity : Measured by its ability to inhibit the M-CSF-induced proliferation of NFS-60 mouse myelogenous leukemia lymphoblast cells. Halenbeck, R. et al. (1989) Biotechnology 7:710.The ED50 for this effect is typically 0.004 – 0.012 µg/mL in the presence of 1 ng/mL of rhM-CSF. | Molecular Mass : Recombinant Human CSF1R, Fc Chimera has a calculated MW of 81 kDa (monomer). In SDS-PAGE migrates as 150 kDa, reducing conditions. | Purity : >97%, by SDS-PAGE under reducing conditions and visualized by silver stain. | Storage : Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). | Reconstitution : Reconstitute at 10 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.