Recombinant Human CD97 Protein, GST-Tagged

Specification :
| Description : This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 107.36 kDa | AA Sequence : MGGRVFLAFCVWLTLPGAETQDSRG CARWCPQNSSCVNATACRCNPGFSS FSEIITTPTETCDDINECATPSKVS CGKFSDCWNTEGSYDCVCSPGYEPV SGAKTFKNESENTCQDVDECSSGRH QCDSSTVCFNTVGSYSCRCRPGWKP RHGIPNNQKDTVCEDMTFSTWTPPP GVHSQTLSRFFDKVQDLGRDSKTSS AEVTIQNVIKLVDELMEAPGDVEAL APPVRHLIATQLLSNLEDIMRILAK SLPKGPFTYISPSNTELTLMIQERG DKNVTMGQSSARMKLNWAVAAGAED PGPAVAGILSIQNMTTLLANASLNL HSKKQAELEEIYESSIRGVQLRRLS AVNSIFLSHNNTKELNSPILFAFSH LESSDGEAGRDPPAKDVMPGPRQEL LCAFWKSDSDRGGHWATEGCQVLGS KNGSTTCQCSHLSSFAILMAHYDVE DWKLTLITRVGLALSLFCLLLCILT FLLVRPIQGSRTTIHLHLCICLFVG STIFLAGIENEGGQVGLRCRLVAGL LHYCFLAAFCWMSLEGLELYFLVVR VFQGQGLSTRWLCLIGYGVPLLIVG VSAAIYSKGYGRPRYCWLDFEQGFL WSFLGPVTFIILCNAVIFVTTVWKL TQKFSEINPDMKKLKKARALTITAI AQLFLLGCTWVFGLFIFDDRSLVLT YVFTILNCLQGAFLYLLHCLLNKKV REEYRKWACLVAGGSKYSEFTSTTS GTGHNQTRALRASESGI | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.