Name :
Active Recombinant Human CSF3R
Specification :
| Description : Human Granulocyte Colony Stimulating Factor (G-CSF) contains internal disulfide bonds. Among the family of colony-stimulating factors, Granulocyte Colony Stimulating Factor (G-CSF) is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of Granulocyte Colony Stimulating Factor (G-CSF) can be induced by bacterial endotoxins, TNF, Interleukin-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of Granulocyte Colony Stimulating Factor (G-CSF). In epithelial, endothelial, and fibroblastic cells, the secretion of Granulocyte Colony Stimulating Factor (G-CSF) is induced by Interleukin-17. | Source : CHO Cells | Species : Human | Form : Lyophilized after extensive dialysis against PBS. | Bio-activity : ED501 x 107 units/mg. | Molecular Mass : 18.7kDa, observed by non-reducing SDS-PAGE. | AA Sequence : Thr27-Pro200. | Endotoxin : | Purity : >95% as analyzed by SDS-PAGE and HPLC. | Storage : Lyophilized recombinant protein remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhG-CSF should be stable up to 1 week at 4°C or up to 2 months at -20°C. | Reconstitution : Reconstituted in ddH2O or PBS at 100 μg/ml.
Gene Information :
| Gene Name : CSF3R colony stimulating factor 3 receptor (granulocyte) [ Homo sapiens ] | Official Symbol : CSF3R | Synonyms : CSF3R; colony stimulating factor 3 receptor (granulocyte); CD114; granulocyte colony-stimulating factor receptor; GCSFR; G-CSF-R; CD114 antigen; G-CSF receptor; | Gene ID : 1441 | mRNA Refseq : NM_000760 | Protein Refseq : NP_000751 | MIM : 138971 | UniProt ID : Q99062 | Chromosome Location : 1p35-p34.3 | Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; Pathways in cancer, organism-specific biosystem; | Function : cytokine receptor activity; receptor activity;
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