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Name :
Recombinant Human CDK11B Protein, GST-tagged

Specification :
| Description : This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 37.84 kDa | AA Sequence : KRFGALLSDQGFDLMNKFLTYFPGR RISAEDGLKHEYFRETPLPIDPSMF PTWPAKSEQQRVKRGTSPRPPEGGL GYSQLGDDDLKETGFHLTTTNQGAS AAGPGFSLKF | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information :
| Gene Name : CDK11B cyclin dependent kinase 11B [ Homo sapiens (human) ] | Official Symbol : CDK11B | Synonyms : CDC2L1; CDK11B; cyclin dependent kinase 11B; p58; PK58; CDK11; CLK-1; CDC2L1; PITSLREA; p58CLK-1; CDK11-p46; CDK11-p58; p58CDC2L1; CDK11-p110; cyclin-dependent kinase 11B; CDC-related protein kinase p58; PITSLRE serine/threonine-protein kinase CDC2L1; cell division cycle 2-like 1 (PITSLRE proteins); cell division protein kinase 11B; galactosyltransferase-associated protein kinase p58/GTA; p58 CLK-1; EC 2.7.11.22 | Gene ID : 984 | mRNA Refseq : NM_001291345 | Protein Refseq : NP_001278274 | MIM : 176873 | UniProt ID : P21127

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors