Name :
Recombinant Human CDK13/Cyclin K protein, GST-tagged
Specification :
| Description : CDK13 or cyclin-dependent kinase 13 is a member of the cyclin-dependent serine/threonine protein kinase family which are well known for their essential roles as master switches in cell cycle control. CDK13 forms a complex with cyclin K and is predicted to play a role in gene regulation. CDK13 may play a role in mRNA processing and is thought to be involved in regulation of hematopoiesis. The CYCK-CDK12 and CYCK-CDK13 complexes display unique function in cell cycle and gene regulation. | Source : Insect cells | Species : Human | Tag : GST | Form : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | Molecular Mass : CDK13 ~160 kDa and Cyclin K ~67 kDa | Protein length : CDK13 (516-end) and Cyclin K (Full Length) | Purity : >70% | Applications : Western Blot | Stability : 1 year at -70 centigrade from date of shipment | Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. | Concentration : 0.1 ug/uL
Gene Information :
| Gene Name : CDK13 cyclin-dependent kinase 13 [ Homo sapiens ] | Official Symbol : CDK13 | Synonyms : CDK13; cyclin-dependent kinase 13; CDC2L5, cell division cycle 2 like 5 (cholinesterase related cell division controller); CDC2L; CHED; cholinesterase related cell division controller; KIAA1791; CDC2-related protein kinase 5; cell division protein kinase 13; cell division cycle 2-like protein kinase 5; cholinesterase-related cell division controller; CDC2L5; hCDK13; FLJ35215; | Gene ID : 8621 | mRNA Refseq : NM_003718 | Protein Refseq : NP_003709 | MIM : 603309 | UniProt ID : Q14004 | Chromosome Location : 7p14.1 | Function : ATP binding; RNA polymerase II carboxy-terminal domain kinase activity; cyclin binding; cyclin-dependent protein kinase activity; nucleotide binding; protein binding; protein kinase activity;
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