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Name :
Recombinant Human CDK20 protein, GST-tagged

Specification :
| Description : CDK20 or cyclin-dependent kinase 20 contains a kinase domain most closely related to the cyclin-dependent protein kinases which may activate cyclin-dependent kinase 2 and is involved in cell growth. CDK20 is a monomeric CAK that specifically phosphorylates CDK2 thr160 and functions as a CDK2-activating kinase. CDK20 is also a novel cyclin-dependent kinase-activating kinase in mammalian cells. CDK20 depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner. | Source : Insect cells | Species : Human | Tag : GST | Form : 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | Molecular Mass : ~64 kDa | Purity : >80% | Applications : Western Blot | Stability : 1 year at -70 centigrade from date of shipment | Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. | Concentration : 0.1 ug/uL

Gene Information :
| Gene Name : CDK20 cyclin-dependent kinase 20 [ Homo sapiens ] | Official Symbol : CDK20 | Synonyms : CDK20; cyclin-dependent kinase 20; CCRK, cell cycle related kinase; p42; CAK-kinase p42; CDK-activating kinase p42; cell cycle-related kinase; cell division protein kinase 20; cyclin-dependent protein kinase H; cyclin-kinase-activating kinase p42; P42; CCRK; CDCH; PNQALRE; | Gene ID : 23552 | mRNA Refseq : NM_001039803 | Protein Refseq : NP_001034892 | MIM : 610076 | UniProt ID : Q8IZL9 | Chromosome Location : 9q22.1 | Function : ATP binding; cyclin-dependent protein kinase activity; nucleotide binding;

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Author: Cholesterol Absorption Inhibitors