Active Recombinant Human CDK5&p35 protein, GST-tagged

Specification :
| Description : CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes – from adhesion and motility, to synaptic plasticity and drug addiction. | Source : Insect cells | Species : Human | Tag : GST | Form : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | Bio-activity : 180 nmol/min/mg | Molecular Mass : ~59 kDa/~60 kDa | Purity : >85% | Applications : Kinase Assay, Western Blot | Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. | Concentration : 0.1μg/μl | Shipping : dry ice