Name :
Recombinant Human CEACAM1 Protein (Gln35-Glu320), His tagged
Specification :
| Description : Isoform 1:Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesis. Its coinhibitory receptor function is phosphorylation- and PTPN6 -dependent, which in turn, suppress signal transduction of associated receptors by dephosphorylation of their downstream effectors. Plays a role in immune response, of T cells, natural killer (NK) and neutrophils.Isoform 8: Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Promotes populations of T cells regulating IgA production and secretion associated with control of the commensal microbiota and resistance to enteropathogens. | Source : E. coli | Species : Human | Tag : His | Form : Lyophilized powder/frozen liquid | Molecular Mass : 31.95 kDa | Protein Length : Gln35-Glu320 | Purity : >90% as determined by SDS-PAGE. | Notes : For research use only. | Storage : Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 centigrade for one week.Store at -20 to -80 centigrade for twelve months from the date of receipt. | Storage Buffer : Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. | Reconstitution : Reconstitute in sterile water for a stock solution. | Shipping : They are shipped out with dry ice/blue ice unless customers require otherwise.
Gene Information :
| Gene Name : CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) [ Homo sapiens (human) ] | Official Symbol : CEACAM1 | Synonyms : CEACAM1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); BGP; carcinoembryonic antigen-related cell adhesion molecule 1; BGP1; CD66a; antigen CD66; CD66a antigen; BGPI; | Gene ID : 634 | mRNA Refseq : NM_001024912 | Protein Refseq : NP_001020083 | MIM : 109770 | UniProt ID : P13688
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