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Name :
Recombinant Human CLEC12A Protein

Specification :
| Description : This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011] | Source : Wheat Germ | Species : Human | Form : Liquid | Molecular Mass : 29.2 kDa | AA Sequence : MSEEVTYADLQFQNSSEMEKIPEIG KFGEKAPPAPSHVWRPAALFLTLLC LLLLIGLGVLASMFHVTLKIEMKKM NKLQNISEELQRNISLQLMSNMNIS NKIRNLSTTLQTIATKLCRELYSKE QEHKCKPCPRRWIWHKDSCYFLSDD VQTWQESKMACAAQNASLLKINNKN ALEFIKSQSRSYDYWLGLSPEEDST RGMRVDNIINSSAWVIRNAPDLNNM YCGYINRLYVQYYHCTYKQRMICEK MANPVQLGSTYFREA | Applications : Antibody ProductionFunctional StudyCompound Screening | Usage : Heating may cause protein aggregation. Please do not heat this product before electrophoresis. | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information :
| Gene Name : CLEC12A C-type lectin domain family 12, member A [ Homo sapiens ] | Official Symbol : CLEC12A | Synonyms : CLEC12A; C-type lectin domain family 12, member A; C-type lectin domain family 12 member A; CLL 1; MICL; C-type lectin superfamily; C-type lectin protein CLL-1; C-type lectin-like molecule-1; dendritic cell-associated lectin 2; myeloid inhibitory C-type lectin-like receptor; CLL1; CLL-1; DCAL-2; MGC70602; | Gene ID : 160364 | mRNA Refseq : NM_001207010 | Protein Refseq : NP_001193939 | MIM : 612088 | UniProt ID : Q5QGZ9

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors