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Name :
Recombinant Human CLEC4C Protein (45-213 aa), His-tagged

Specification :
| Description : Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose. | Source : Yeast | Species : Human | Tag : His | Form : Tris-based buffer,50% glycerol | Molecular Mass : 22.0 kDa | Protein length : 45-213 aa | AA Sequence : NFMYSKTVKRLSKLREYQQYHPSLT CVMEGKDIEDWSCCPTPWTSFQSSC YFISTGMQSWTKSQKNCSVMGADLV VINTREEQDFIIQNLKRNSSYFLGL SDPGGRRHWQWVDQTPYNENVTFWH SGEPNNLDERCAIINFRSSEEWGWN DIHCHVPQKSICKMKKIYI | Purity : > 90% as determined by SDS-PAGE. | Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. | Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. | Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information :
| Gene Name : CLEC4C C-type lectin domain family 4, member C [ Homo sapiens ] | Official Symbol : CLEC4C | Synonyms : DLEC; HECL; BDCA2; CD303; CLECSF7; CLECSF11; PRO34150; | Gene ID : 170482 | mRNA Refseq : NM_203503.1 | Protein Refseq : NP_987099.1 | MIM : 606677 | UniProt ID : Q8WTT0

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Author: Cholesterol Absorption Inhibitors