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Name :
Recombinant Human CRTAM Protein, His-tagged

Specification :
| Description : CRTAM, also known as cytotoxic and regulatory T-cell molecule, is a member of the immunoglobulin superfamily that complies with the structural characteristics of the JAM family of proteins and is phylogenetically more closely related to nectin-like proteins. It is a molecule involved in epithelial cell adhesion. This protein interacts with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. | Source : Insect cell | Species : Human | Tag : His | Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. | Molecular Mass : 31.0kDa (278aa)40-57KDa (SDS-PAGE under reducing conditions.) | AA Sequence : SLTNHTETIT VEEGQTLTLK CVTSLRKNSS LQWLTPSGFT IFLNEYPALK NSKYQLLHHS ANQLSITVPN VTLQDEGVYK CLHYSDSVSTKEVKVIVLAT PFKPILEASV IRKQNGEEHV VLMCSTMRSK PPPQITWLLG NSMEVSGGTL HEFETDGKKC NTTSTLIIHT YGKNSTVDCIIRHRGLQGRK LVAPFRFEDL VTDEETASDA LERNSLSSQD PQQPTSTVSV TEDSSTSEID KEEKEQTTQD PDLTTEANPQ YLGLARKKSGLEHHHHHH | Endotoxin : | Purity : >90% by SDS – PAGE | Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. | Concentration : 1mg/ml (determined by Absorbance at 280nm)

Gene Information :
| Gene Name : CRTAM cytotoxic and regulatory T cell molecule [ Homo sapiens ] | Official Symbol : CRTAM | Synonyms : CRTAM; cytotoxic and regulatory T cell molecule; cytotoxic and regulatory T-cell molecule; CD355; class I MHC restricted T cell associated molecule; class-I MHC-restricted T cell associated molecule; class-I MHC-restricted T-cell-associated molecule; | Gene ID : 56253 | mRNA Refseq : NM_019604 | Protein Refseq : NP_062550 | MIM : 612597 | UniProt ID : O95727 | Chromosome Location : 11q24.1 | Pathway : Adaptive Immune System, organism-specific biosystem; Immune System, organism-specific biosystem; Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, organism-specific biosystem; | Function : receptor binding;

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Author: Cholesterol Absorption Inhibitors