Share this post on:

Name :
Recombinant Human CSF2RB Protein, C-His-tagged

Specification :
| Description : The common beta-chain (beta-c) of the granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5 receptors is the major signaling subunit of these receptors, coupling ligand binding to multiple biological activities. Tyrosine phosphorylation of cytokine receptor common beta-chain is one of the first events in GM-CSF, IL-3 and IL-5 receptor activation and in signaling initiation. Serine phosphorylation within the 14-3-3 binding sequence of the common beta-chain is also involved in GM-CSF, IL-3 and IL-5 receptor-specific functions. | Source : E. coli | Species : Human | Tag : C-His | Molecular Mass : ~47 kDa | AA Sequence : WERSLAGAEETIPLQTLRCYNDYTS HITCRWADTQDAQRLVNVTLIRRVN EDLLEPVSCDLSDDMPWSACPHPRC VPRRCVIPCQSFVVTDVDYFSFQPD RPLGTRLTVTLTQHVQPPEPRDLQI STDQDHFLLTWSVALGSPQSHWLSP GDLEFEVVYKRLQDSWEDAAILLSN TSQATLGPEHLMPSSTYVARVRTRL APGSRLSGRPSKWSPEVCWDSQPGD EAQPQNLECFFDGAAVLSCSWEVRK EVASSVSFGLFYKPSPDAGEEECSP VLREGLGSLHTRHHCQIPVPDPATH GQYIVSVQPRRAEKHIKSSVNIQMA PPSLNVTKDGDSYSLRWETMKMRYE HIDHTFEIQYRKDTATWKDSKTETL QNAHSMALPALEPSTRYWARVRVRT SRTGYNGIWSEWSEARSWDTESVLP MW | Purity : Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). | Notes : For research use only, not for use in diagnostic procedure. | Storage : Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. | Concentration : ≥0.5 mg/mL | Storage Buffer : PBS, 4M Urea, pH7.4

Gene Information :
| Gene Name : CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) [ Homo sapiens (human) ] | Official Symbol : CSF2RB | Synonyms : CSF2RB; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); IL3RB; cytokine receptor common subunit beta; CD131; IL5RB; GM-CSF/IL-3/IL-5 receptor common beta-chain; GM-CSF/IL-3/IL-5 receptor common beta subunit; colony-stimulating factor-2 receptor, beta, low-affinity; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); SMDP5; CDw131; | Gene ID : 1439 | mRNA Refseq : NM_000395 | Protein Refseq : NP_000386 | MIM : 138981 | UniProt ID : P32927

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
PEDF Protein
IFN-alpha 14/IFNA14 Protein
Popular categories:
PDGF-AA
Contactin-4

Share this post on:

Author: Cholesterol Absorption Inhibitors