Name :
Active Recombinant Human DPP4 protein, His-tagged
Specification :
| Description : The protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. | Source : E. coli | Species : Human | Tag : His | Form : In 20 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, pH 8.0 (10% glycerol) | Bio-activity : Approximately > 50 Unit/mg. | Molecular Mass : 86.4 kDa | AA Sequence : ADPRKTYTLTDYLKNTYRLKLYSLR WISDHEYLYKQENNILVFNAEYGNS SVFLENSTFDEFGHSINDYSISPDG QFILLEYNYVKQWRHSYTASYDIYD LNKRQLITEERIPNNTQWVTWSPVG HKLAYVWNNDIYVKIEPNLPSYRIT WTGKEDIIYNGITDWVYEEEVFSAY SALWWSPNGTFLAYAQFNDTEVPLI EYSFYSDESLQYPKTVRVPYPKAGA VNPTVKFFVVNTDSLSSVTNATSIQ ITAPASMLIGDHYLCDVTWATQERI SLQWLRRIQNYSVMDICDYDESSGR WNCLVARQHIEMSTTGWVGRFRPSE PHFTLDGNSFYKIISNEEGYRHICY FQIDKKDCTFITKGTWEVIGIEALT SDYLYYISNEYKGMPGGRNLYKIQL SDYTKVTCLSCELNPERCQYYSVSF SKEAKYYQLRCSGPGLPLYTLHSSV NDKGLRVLEDNSALDKMLQNVQMPS KKLDFIILNETKFWYQMILPPHFDK SKKYPLLLDVYAGPCSQKADTVFRL NWATYLASTENIIVASFDGRGSGYQ GDKIMHAINRRLGTFEVEDQIEAAR QFSKMGFVDNKRIAIWGWSYGGYVT SMVLGSGSGVFKCGIAVAPVSRWEY YDSVYTERYMGLPTPEDNLDHYRNS TVMSRAENFKQVEYLLIHGTADDNV HFQQSAQISKALVDVGVDFQAMWYT DEDHGIASSTAHQHIYTHMSHFIKQ CFSLP-SGRLVPRGSHHHHHH | Endotoxin : | Purity : > 95% by SDS-PAGE | Unit Definition : One unit will hydrolyze 1 umole of p-nitroaniline per minute at pH 8.0 at 37 centigrade using 1mM of Gly-Pro p-nitroanilde as a substrate. | Applications : Functional Study; SDS-PAGE | Storage : Store at 4 centigrade for 1-2 weeks. For long term storage store at -20 centigrade or -80 centigrade.Aliquot to avoid repeated freezing and thawing. | Concentration : 0.5 mg/mL
Gene Information :
| Gene Name : DPP4 dipeptidyl-peptidase 4 [ Homo sapiens ] | Official Symbol : DPP4 | Synonyms : DPP4; dipeptidyl-peptidase 4; ADCP2, adenosine deaminase complexing protein 2 , CD26, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); dipeptidyl peptidase 4; DPPIV; ADCP-2; DPP IV; dipeptidylpeptidase 4; dipeptidyl peptidase IV; T-cell activation antigen CD26; adenosine deaminase complexing protein 2; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); CD26; ADABP; ADCP2; TP103; | Gene ID : 1803 | mRNA Refseq : NM_001935 | Protein Refseq : NP_001926 | MIM : 102720 | UniProt ID : P27487 | Chromosome Location : 2q23-qter | Pathway : Incretin Synthesis, Secretion, and Inactivation, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Protein digestion and absorption, organism-specific biosystem; Protein digestion and absorption, conserved biosystem; Regulation of Insulin Secretion, organism-specific biosystem; Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1), organism-specific biosystem; | Function : aminopeptidase activity; collagen binding; dipeptidyl-peptidase activity; peptidase activity; peptide binding; protease binding; protein binding; protein homodimerization activity; receptor activity; receptor binding; serine-type endopeptidase activity; serine-type peptidase activity;
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