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Name :
Active Recombinant Human DPP4 protein, His-tagged

Specification :
| Description : The protein encoded by this gene is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. | Source : E. coli | Species : Human | Tag : His | Form : In 20 mM Tris-HCl, 100 mM NaCl, 1 mM EDTA, pH 8.0 (10% glycerol) | Bio-activity : Approximately > 50 Unit/mg. | Molecular Mass : 86.4 kDa | AA Sequence : ADPRKTYTLTDYLKNTYRLKLYSLR WISDHEYLYKQENNILVFNAEYGNS SVFLENSTFDEFGHSINDYSISPDG QFILLEYNYVKQWRHSYTASYDIYD LNKRQLITEERIPNNTQWVTWSPVG HKLAYVWNNDIYVKIEPNLPSYRIT WTGKEDIIYNGITDWVYEEEVFSAY SALWWSPNGTFLAYAQFNDTEVPLI EYSFYSDESLQYPKTVRVPYPKAGA VNPTVKFFVVNTDSLSSVTNATSIQ ITAPASMLIGDHYLCDVTWATQERI SLQWLRRIQNYSVMDICDYDESSGR WNCLVARQHIEMSTTGWVGRFRPSE PHFTLDGNSFYKIISNEEGYRHICY FQIDKKDCTFITKGTWEVIGIEALT SDYLYYISNEYKGMPGGRNLYKIQL SDYTKVTCLSCELNPERCQYYSVSF SKEAKYYQLRCSGPGLPLYTLHSSV NDKGLRVLEDNSALDKMLQNVQMPS KKLDFIILNETKFWYQMILPPHFDK SKKYPLLLDVYAGPCSQKADTVFRL NWATYLASTENIIVASFDGRGSGYQ GDKIMHAINRRLGTFEVEDQIEAAR QFSKMGFVDNKRIAIWGWSYGGYVT SMVLGSGSGVFKCGIAVAPVSRWEY YDSVYTERYMGLPTPEDNLDHYRNS TVMSRAENFKQVEYLLIHGTADDNV HFQQSAQISKALVDVGVDFQAMWYT DEDHGIASSTAHQHIYTHMSHFIKQ CFSLP-SGRLVPRGSHHHHHH | Endotoxin : | Purity : > 95% by SDS-PAGE | Unit Definition : One unit will hydrolyze 1 umole of p-nitroaniline per minute at pH 8.0 at 37 centigrade using 1mM of Gly-Pro p-nitroanilde as a substrate. | Applications : Functional Study; SDS-PAGE | Storage : Store at 4 centigrade for 1-2 weeks. For long term storage store at -20 centigrade or -80 centigrade.Aliquot to avoid repeated freezing and thawing. | Concentration : 0.5 mg/mL

Gene Information :
| Gene Name : DPP4 dipeptidyl-peptidase 4 [ Homo sapiens ] | Official Symbol : DPP4 | Synonyms : DPP4; dipeptidyl-peptidase 4; ADCP2, adenosine deaminase complexing protein 2 , CD26, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); dipeptidyl peptidase 4; DPPIV; ADCP-2; DPP IV; dipeptidylpeptidase 4; dipeptidyl peptidase IV; T-cell activation antigen CD26; adenosine deaminase complexing protein 2; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); CD26; ADABP; ADCP2; TP103; | Gene ID : 1803 | mRNA Refseq : NM_001935 | Protein Refseq : NP_001926 | MIM : 102720 | UniProt ID : P27487 | Chromosome Location : 2q23-qter | Pathway : Incretin Synthesis, Secretion, and Inactivation, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem; Protein digestion and absorption, organism-specific biosystem; Protein digestion and absorption, conserved biosystem; Regulation of Insulin Secretion, organism-specific biosystem; Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1), organism-specific biosystem; | Function : aminopeptidase activity; collagen binding; dipeptidyl-peptidase activity; peptidase activity; peptide binding; protease binding; protein binding; protein homodimerization activity; receptor activity; receptor binding; serine-type endopeptidase activity; serine-type peptidase activity;

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors