Recombinant Human CTLA4 Protein (Gln36-Ser161), C-hFc-tagged

Specification :
| Description : This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. | Source : HEK293 | Species : Human | Tag : C-hFc | Form : Lyophilized | Molecular Mass : 39.6 kDa | Protein Length : Gln36-Ser161 | Purity : > 95% as determined by SDS-PAGE and Coomassie blue staining. | Storage : Store at -80 centigrade for 12 months (Avoid repeated freezing and thawing) | Storage Buffer : Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 87 % trehalose is added as protectants before lyophilization.