Recombinant Human CTLA4 protein, His-tagged

Specification :
| Description : CTLA4, also known as cytotoxic T-lymphocyte-associated protein 4, is a co-inhibitory molecule expressed on T cells that mediates the inhibition of T-cell function. This protein is a crucial immune regulator that mediates both negative costimulation signals to T cells, and regulatory T (Treg)-cell extrinsic control of effector responses. It has been implicated in several autoimmune diseases, such as systemic lupus erythematosus. | Source : Insect cells | Species : Human | Tag : His tag | Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 20% glycerol. | Molecular Mass : 14.6kDa (135aa)18-28KDa (SDS–PAGE under reducing conditions.) | AA Sequence : ADLKAMHVAQ PAVVLASSRG IASFVCEYAS PGKATEVRVT VLRQADSQVT EVCAATYMMG NELTFLDDSI CTGTSSGNQV NLTIQGLRAM DTGLYICKVE LMYPPPYYLG IGNGTQIYVI DPEPCPDSDH HHHHH | Endotoxin : | Purity : >90% by SDS – PAGE | Storage : Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles. | Concentration : 0.25mg/ml (determined by Absorbance at 280nm)