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Name :
Recombinant Human CXCR1 Protein, GST-tagged

Specification :
| Description : The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008] | Source : Wheat Germ | Species : Human | Tag : GST | Molecular Mass : 64.24 kDa | AA Sequence : MSNITDPQMWDFDDLNFTGMPPADE DYSPCRLETETLNKYVVIIAYALVF LLSLLGNSLVMLVILYSRVGRSVTD VYLLNLALADLLFALTLPIWAASKV NGWIFGTFLCKVVSLLKEVNFYSGI LLLACISVDRYLAIVHATRTLTQKR HLVKFVCLGCWGLSMNLSLPFFLFR QAYHPNNSSPVCYEVLGNDTAKWRM VLRILPHTFGFIVPLFVMLFCYGFT LRTLFKAHMGQKHRAMRVIFAVVLI FLLCWLPYNLVLLADTLMRTQVIQE SCERRNNIGRALDATEILGFLHSCL NPIIYAFIGQNFRHGFLKILAMHGL VSKEFLARHCVTSYTSSSVNVSSNL | Applications : Enzyme-linked Immunoabsorbent AssayWestern Blot (Recombinant protein)Antibody ProductionProtein Array | Notes : Best use within three months from the date of receipt of this protein. | Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. | Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information :
| Gene Name : CXCR1 chemokine (C-X-C motif) receptor 1 [ Homo sapiens ] | Official Symbol : CXCR1 | Synonyms : CXCR1; chemokine (C-X-C motif) receptor 1; CMKAR1, IL8RA, interleukin 8 receptor, alpha; C-X-C chemokine receptor type 1; CD181; CDw128a; CKR 1; CXC-R1; CXCR-1; IL-8R A; IL-8 receptor type 1; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A; high affinity interleukin-8 receptor A; C-C; CD128; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; C-C-CKR-1; | Gene ID : 3577 | mRNA Refseq : NM_000634 | Protein Refseq : NP_000625 | MIM : 146929 | UniProt ID : P25024

MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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Author: Cholesterol Absorption Inhibitors