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Name :
Recombinant Human CYLD Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : This gene is encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 107 kDa | AA Sequence : MSSGLWSQEKVTSPYWEERIFYLLL QECSVTDKQTQKLLKVPKGSIGQYI QDRSVGHSRIPSAKGKKNQIGLKIL EQPHAVLFVDEKDVVEINEKFTELL LAITNCEERFSLFKNRNRLSKGLQI DVGCPVKVQLRSGEEKFPGVVRFRG PLLAERTVSGIFFGVELLEEGRGQG FTDGVYQGKQLFQCDEDCGVFVALD KLELIEDDDTALESDYAGPGDTMQV ELPPLEINSRVSLKVGETIESGTVI FCDVLPGKESLGYFVGVDMDNPIGN WDGRFDGVQLCSFACVESTILLHIN DIIPESVTQERRPPKLAFMSRGVGD KGSSSHNKPKATGSTSDPGNRNRSE LFYTLNGSSVDSQPQSKSKNTWYID EVAEDPAKSLTEISTDFDRSSPPLQ PPPVNSLTTENRFHSLPFSLTKMPN TNGSIGHSPLSLSAQSVMEELNTAP VQESPPLAMPPGNSHGLEVGSLAEV KENPPFYGVIRWIGQPPGLNEVLAG LELEDECAGCTDGTFRGTRYFTCAL KKALFVKLKSCRPDSRFASLQPVSN QIERCNSLAFGGYLSEVVEENTPPK MEKEGLEIMIGKKKGIQGHYNSCYL DSTLFCLFAFSSVLDTVLLRPKEKN DVEYYSETQELLRTEIVNPLRIYGY VCATKIMKLRKILEKVEAASGFTSE EKDPEEFLNILFHHILRVEPLLKIR SAGQKVQDCYFYQIFMEKNEKVGVP TIQQLLEWSFINSNLKFAEAPSCLI IQMPRFGKDFKLFKKIFPSLELNIT DLLEDTPRQCRICGGLAMYECRECY DDPDISAGKIKQFCKTCNTQVHLHP KRLNHKYNPVSLPKDLPDWDWRHGC IPCQNMELFAVLCIETSHYVAFVKY GKDDSAWLFFDSMADRDGGQNGFNI PQVTPCPEVGEYLKMSLEDLHSLDS RRIQGCARRLLCDAYMCMYQSPTMS LYKTRTRPLEQKLISEEDLAANDIL DYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information :
| Gene Name : CYLD CYLD lysine 63 deubiquitinase [ Homo sapiens (human) ] | Official Symbol : CYLD | Synonyms : CYLD; cylindromatosis (turban tumor syndrome); CYLD1; ubiquitin carboxyl-terminal hydrolase CYLD; KIAA0849; ubiquitin specific peptidase like 2; USPL2; ubiquitin thioesterase CYLD; deubiquitinating enzyme CYLD; ubiquitin thiolesterase CYLD; ubiquitin-specific-processing protease CYLD; probable ubiquitin carboxyl-terminal hydrolase CYLD; EAC; MFT; SBS; TEM; BRSS; CDMT; MFT1; CYLDI; HSPC057; FLJ20180; FLJ31664; FLJ78684; | Gene ID : 1540 | mRNA Refseq : NM_001042355 | Protein Refseq : NP_001035814 | MIM : 605018 | UniProt ID : Q9NQC7

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Author: Cholesterol Absorption Inhibitors