Recombinant Human DCK Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 30.5 kDa | AA Sequence : MATPPKRSCPSFSASSEGTRIKKIS IEGNIAAGKSTFVNILKQLCEDWEV VPEPVARWCNVQSTQDEFEELTMSQ KNGGNVLQMMYEKPERWSFTFQTYA CLSRIRAQLASLNGKLKDAEKPVLF FERSVYSDRYIFASNLYESECMNET EWTIYQDWHDWMNNQFGQSLELDGI IYLQATPETCLHRIYLRGRNEEQGI PLEYLEKLHYKHESWLLHRTLKTNF DYLQEVPILTLDVNEDFKDKYESLV EKVKEFLSTLTRTRPLEQKLISEED LAANDILDYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.