Recombinant Human DCTN2 Protein, Myc/DDK-tagged, C13 and N15-labeled

Specification :
| Description : This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. | Source : HEK293 | Species : Human | Tag : Myc/DDK | Molecular Mass : 44.6 kDa | AA Sequence : MADPKYADLPGIARNEPDVYETSDL PEDDQAEFDAFAQELEELTSTSVEH IIVNPNAAYDKFKDKRVGTKGLDFS DRIGKTKRTGYESGEYEMLGEGLGV KETPQQKYQRLLHEVQELTTEVEKI KTTVKESATEEKLTPVLLAKQLAAL KQQLVASHLEKLLGPDAAINLTDPD GALAKRLLLQLEATKNSKGGSGGKT TGTPPDSSLVTYELHSRPEQDKFSQ AAKVAELEKRLTELETAVRCDQDAQ NPLSAGLQGACLMETVELLQAKVSA LDLAVLDQVEARLQSVLGKVNEIAK HKASVEDADTQSKVHQLYETIQRWS PIASTLPELVQRLVTIKQLHEQAMQ FGQLLTHLDTTQQMIANSLKDNTTL LTQVQTTMRENLATVEGNFASIDER MKKLGKTRTRPLEQKLISEEDLAAN DILDYKDDDDKV | Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining | Stability : Stable for 3 months from receipt of products under proper storage and handling conditions. | Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. | Concentration : 50 μg/mL as determined by BCA | Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.